A sample DESeqResults object — res_macrophage_IFNg_vs

A sample DESeqResults object, generated in the DESeq2 framework

Format

A DESeqResults object

Source

Details on how this object has been created are included in the create_mosdef_data.R script, included in the (installed) inst/scripts folder of the mosdef package. This is also available at https://github.com/imbeimainz/mosdef/blob/devel/inst/scripts/create_mosdef_data.R

Details

This DESeqResults object is on the data from the macrophage package. This result set has been created by setting the design to ~line + condition to detect the effect of the condition while accounting for the different cell lines included.

Specifically, this object contains the differences between the IFNg vs naive samples, testing against a logFC threshold of 1 for robustness.

References

Alasoo, et al. "Shared genetic effects on chromatin and gene expression indicate a role for enhancer priming in immune response", Nature Genetics, January 2018 doi: 10.1038/s41588-018-0046-7.